No differences in membrane properties of ventral CA1 and dorsal CA1 pyramidal neurons were observed between controls and after BLA inactivation following inhibitory avoidance learning. Input resistance, sag, resting potential, spike width, and action potential amplitude values represent means ± SEM.
Article: Learning-dependent plasticity of hippocampal CA1 pyramidal neuron postburst afterhyperpolarizations and increased excitability after inhibitory avoidance learning depend upon basolateral amygdala inputs.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Farmer GE; Thompson LT Hippocampus, 2012
Rats | Cells | Input resistance | Sag | Resting potential | Spike width | AP amplitude | |
---|---|---|---|---|---|---|---|
(n) | (n) | (MΩ) | (mV) | (mV) | (mV) | (mV) | |
CA1v | |||||||
Control | 19 | 29 | 35.5 ± 1.9 | 6.2 ± 0.4 | −66.8 ± 0.9 | 1.3 ± 0.02 | 86.0 ± 1.2 |
Trained 1 h | 22 | 37 | 41.0 ± 1.9 | 6.2 ± 0.4 | −65.4 ± 0.9 | 1.3 ± 0.02 | 84.5 ± 0.8 |
Saline 1 h | 2 | 6 | 53.4 ± 4.0 | 8.0 ± 1.4 | −69.6 ± 1.2 | 1.4 ± 0.04 | 89.3 ± 0.8 |
Lidocaine 1 h | 2 | 5 | 38.9 ± 4.7 | 8.5 ± 0.2 | −67.2 ± 3.5 | 1.3 ± 0.03 | 86.7 ± 1.5 |
Bupivacaine 1 h | 1 | 3 | 46.6 ± 13.4 | 8.2 ± 1.9 | −69.6 ± 1.9 | 1.3 ± 0.03 | 88.1 ± 1.0 |
Context Inactivation 1 h | 2 | 9 | 42.3 ± 2.6 | 7.9 ± 0.7 | −68.1 ± 0.3 | 1.3 ± 0.02 | 87.2 ± 0.9 |
Trained 24 h | 5 | 14 | 41.8 ± 1.6 | 5.7 ± 0.6 | −66.7 ± 1.2 | 1.4 ± 0.02 | 84.4 ± .08 |
Saline 24 h | 3 | 8 | 52.5 ± 2.5 | 9.5 ± 0.4 | −67.8 ± 1.3 | 1.5 ± 0.05 | 83.5 ± 0.9 |
Lidocaine 24 h | 4 | 7 | 41.8 ± 2.4 | 9.0 ± 0.6 | −67.4 ± 3.5 | 1.2 ± 0.01 | 86.5 ± 0.7 |
Bupivacaine 24 h | 7 | 17 | 40.4 ± 2.7 | 9.0 ± 0.4 | −67.5 ± 1.3 | 1.3 ± 0.02 | 88.0 ± 0.8 |
CA1d | |||||||
Control | 8 | 12 | 40.9 ± 1.5 | 8.3 ± 0.5 | −65.6 ± 1.6 | 1.2 ± 0.02 | 83.0 ± 2.5 |
Trained 1 h | 9 | 15 | 37.5 ± 2.2 | 8.3 ± 0.6 | −65.9 ± 1.2 | 1.3 ± 0.02 | 86.0 ± 1.0 |
Saline 1 h | 3 | 6 | 42.6 ± 0.0 | 8.0 ± 0.7 | −67.7 ± 0.7 | 1.3 ± 0.03 | 87.3 ± 1.3 |
Lidocaine 1 h | 2 | 6 | 36.3 ± 5.1 | 6.4 ± 0.7 | −67.6 ± 3.1 | 1.3 ± 0.02 | 86.7 ± 1.5 |
Bupivacaine 1 h | 1 | 3 | 42.4 ± 0.0 | 6.6 ± 0.6 | −67.4 ± 2.9 | 1.3 ± 0.01 | 85.1 ± 1.3 |
Trained 24 h | 6 | 14 | 36.7 ± 2.8 | 9.4 ± 0.7 | −66.7 ± 1.0 | 1.3 ± 0.01 | 88.2 ± 0.8 |
Saline 24 h | 5 | 15 | 42.3 ± 2.7 | 7.9 ± 0.7 | −68.9 ± 1.0 | 1.3 ± 0.01 | 85.3 ± 0.8 |
Lidocaine 24 h | 5 | 18 | 43.5 ± 3.8 | 7.1 ± 0.4 | −64.2 ± 2.5 | 1.4 ± 0.02 | 88.6 ± 0.6 |
Bupivacaine 24 h | 7 | 18 | 39.1 ± 2.9 | 8.2 ± 0.4 | −69.2 ± 1.6 | 1.2 ± 0.02 | 87.6 ± 0.5 |